Pyrethroid pesticide poisoning emergency

Pyrethroids are a class of insecticides commonly used in agricultural production, especially pest control. The commonly used pyrethroid pesticides include deltamethrin, cypermethrin, permethrin, tetramethrin, fenthrin, etc. They are mostly low-to-medium toxic pesticides. They are relatively safe for humans and animals, but they cannot ignore the safety regulations. Otherwise it will cause poisoning. This type of pesticide is a nerve agent that acts on the nerve membrane, which can change the permeability of the nerve membrane and interfere with nerve conduction to produce poisoning. However, these pesticides can hydrolyze and oxidize under the action of mammalian liver enzymes, and most of the metabolites can be excreted quickly.
(1) symptoms of poisoning 1 oral poisoning symptoms. The mild symptoms of oral poisoning are headache, dizziness, nausea and vomiting, burning sensation in the upper abdomen, fatigue, loss of appetite, chest tightness, and runny nose. Symptoms of moderate poisoning, in addition to the above-mentioned symptoms, also manifested in convulsions, increased secretions in the mouth, nose, and trachea, trembling hands, muscle beating, irregular heartbeats, and breathing difficulties. Severe symptoms are dyspnea, purpura, intrapulmonary blisters, paroxysmal convulsions or convulsions in the extremities, loss of consciousness, severe coma or shock in severe cases, and repeated cramps in severe cases cause laryngeal spasm and suffocation.
2 symptoms of transdermal poisoning. The skin is red, hot, itchy, numb, and there are severe rashes, blisters, erosions. After the eyes are affected by pesticides (2) First-aid oral poisoning should immediately induce vomiting and gastric lavage. For those who suffer from transdermal poisoning, they should immediately rinse the skin with soap and water. The dermatitis can be used stove, Ganshi lotion or 2% to 3% boric acid water wet dressing; eyes contaminated with pesticides rinse with plenty of water or saline, oral chlorpheniramine, Diphenhydramine and so on.
(3) There is no special antidote for treatment, only symptomatic treatment can be used.
1 For unstable restlessness, convulsions, convulsions, stability may be 10 to 20 mg intramuscularly or intravenously; or sedatives of phenobarbitone sodium 00.1 to 0.2 g intramuscularly; if necessary, repeated use 4 to 6 hours.
2 Atropine can inhibit saliva secretion in convection water.
3 For those with dyspnea, oxygen should be given, and care should be taken to keep the airway open.
4 pairs of cerebral edema can be used 20% mannitol or 25% sorbitol 250 ml intravenously or intravenously; or dexamethasone 10 ~ 20 ml or 200 mg hydrogenated cortisone add 10% glucose solution 100 ~ 200 ml intravenous infusion.

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