On June 13, 2016, the well-known 3D bioprinting technology company Organovo announced a collaboration with the University of California, San Francisco (UCSF) to develop a 3D bioprinting organization for bone disease research. It is reported that the cooperation between the two organizations was facilitated by the Methuselah Foundation, which is part of the ongoing University 3D Bioprinter Program at the Methuselah Foundation.
It is understood that musculoskeletal diseases are the second leading cause of disability worldwide, and 2.4 out of every 10,000 newborns are affected by genetic skeletal disorders. A better understanding of bone composition and structure for in vitro modeling of bone diseases is essential to drive bone growth and repair drug development.
“Partnerships with world-class research institutions will accelerate our pioneering work in the search for treatments for important diseases and the development of therapeutic implantables,†said Keith Murphy, Chairman and CEO of Organovo. The cooperation with UCSF will combine the technical expertise of both parties, and we are an important step in this research direction. With the support of the Methuselah Foundation, our outstanding researchers will take advantage of Organovo's powerful technology platform to achieve a major breakthrough. â€
“Previously, when we studied bone diseases—such as malignant bone tumors or heterotopic ossification—most of the research was done in a two-dimensional environment—such as a petri dish—we passed this The way to understand the interactions between many cells, but it is not clear how they work on a natural 3D stent." Dr. Edward Hsiao, assistant professor of UCSF Medical School, said: "And 3D bio-printing technology has created better The mechanism combines inorganic scaffolds with living cells, which will have a critical impact on our repair of damaged bone tissue and other tissue structures."
Also participating in the collaboration include labs from UCSF's Tamara Alliston, Chelsea Bahney, Jeff Lotz and Robert Nissenson.
It is understood that under the Methuselah Foundation's University 3D Bioprinter program, the Foundation donated at least $500,000 to the Organovo Bioprint Research Project at several research institutes. The funding will include 3D printer costs as well as some important research budgets.
“The Methuselah Foundation has long been a long-time supporter of academic and industrial research in 3D bioprinting, regenerative medicine, tissue engineering,†said David Gobel, CEO of the Methuselah Foundation. “Our university 3D bioprinter project will make Organovo groundbreaking. The technology of 3D bioprinting is put into the hands of the most intelligent tissue engineering scientists."
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