The medicinal value of Huangjing

Medicinal value

1. Anti-pathogenic micro-organisms: In vitro tests showed that Huang Jingshui extract solution (1:320) has an inhibitory effect on Salmonella typhi, Staphylococcus aureus, and acid-fast bacillus, and 2% borneol has a common pathogenic fungus in Sabouraud medium. Different degrees of inhibition.

2. Effects on Blood Glucose: In rabbits, gavage of Huang Jing extract gradually increased the blood glucose level and then decreased. Huangjing extract has a significant inhibitory effect on epinephrine-induced hyperglycemia.

3. Anti-fatigue effect: Huang Jing decoction 17.67% concentration 0.3ml / only intraperitoneal injection, can extend the swimming time of mice.

4. Antioxidation: Huangjing decoction 20% concentration, 13ml/only feeding, continuous 27 days, so that the liver superoxide dismutase (SOD) activity increased, myocardial lipofuscin content decreased.

5. Anti-aging effects: Huang Jing decoction, 20% soaked mulberry leaves feeding silkworm, has extended the role of silkworm larvae.

6. Hemostasis: methanol extract of Huang Jing 40mg / only, n-butanol part 20mg / only, water layer part 20mg / only, intraperitoneal injection, dry ice-methanol frozen mouse tail 1 minute, cut-tail test showed that the role of hemostasis, so that Reduced bleeding in mice.

7. Effect on cardiovascular: Huang Jing Shui extract 0.16-0.26g/kg intravenous injection, significantly increased coronary flow in anesthetized dogs; 1.5g/kg intravenous injection, antagonistic effect on pituitrin-induced myocardial ischemia in rabbits against pituitary The increase of T wave caused by avervain promotes the early recovery of T wave abnormality; 12 g/kg intraperitoneal injection can enhance the tolerance of mice to hypoxia.

8. Antiviral effect: Huang Jing polysaccharide 0.2% eye drops, 6 times / day, or service Huang polygonum polysaccharide 10mg/kg, 2 times / day, on experimental rabbits with herpes simplex virus keratitis have a therapeutic effect.

9. Other effects: Huang Jing decoction 6g/kg gavage, for 10 consecutive days, can increase the red blood cell membrane Na +, K + -ATP enzyme activity. 40% euphol extract 0.3 ml / only intraperitoneal injection, can improve the mouse myocardial, liver, spleen cells DNA 3H-TdR incorporation rate. The content of cAMP and cGMP in the plasma of Huangjing Decoction (0.5g/kg) decreased, but the cGMP decreased more. Therefore, the ratio of cAMP/cGMP was higher than that of the control group. The contents of cAMP and cGMP in the spleen increased, but cAMP/cGMP increased. No significant change in the ratio.


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