Fish pond cages

In the fish ponds of the southern region, the open cages are used to hold the yellow crickets. The operation is simple, the breeding income is considerable, and the market sales channels are unimpeded. It has become the optimal project for the adjustment of the local agricultural structure and has practical significance for promotion. In March 2004, 10 acres of fish ponds in Nanshan Wu Xiaoming, Lucheng District, Zhangzhou City, were put into 10 open-mouth cages and 150 kg of astragalus seedlings were planted. After 7 months of breeding, 3910 kg of fish were produced in the pond, and the cages were harvested.鳝 420 kg, a total profit of 21,500 yuan, to achieve a double income of fish, turtles, to avoid the risk of aquaculture, and improve yield benefits. The technical points are now described as follows: 1. The cages are made of 60 mesh polyethylene mesh and the specifications are 331.5m; 8 bamboo rods are inserted into the bottom sludge for support, and the cages are fixed and raised 0.5m above the water surface. To prevent jaundice from jumping out of the box, the Internet is tight, the net is slack, and the bottom corners are knotted. Second, water plants mainly use water peanuts, can be used with a small amount of oil grass and water hyacinth; if the oil grass, you do not need to match other plants. Before entering the tank, water should be removed from the water, and the coverage of the tank into the tank should be 90%. If it exceeds 90%, the exchange of gas in the water of the cage will be unfavorable. In the week prior to planting, the water grass was cut into smaller pieces than the cage box area with a guillotine blade and pushed into the cage with bamboo rafts. The growth of aquatic grasses in cages has the effect of purifying water quality. Third, the general choice of a species of general weather is fine, the climate is stable after 3 days, began to receive quail species, the seed survival rate is higher. If the weather is sunny and it is harvested, and the weather changes the next day, soak the tank with drugs until it is fine and then put it in the tank, otherwise the mortality rate can reach over 90%. The species is captured and purchased by the natural river channel, and individuals with no disease or mechanical damage are selected. The quail species should be rigorously selected after soaking and soaking: that is, the quail species sinks into the bottom of the water, and only the fish tail is not seen at the head of the fish. When the gliding wall is patted, there is a frightened reaction, indicating that health can be raised. After one and a half months of feeding, the seeds were sorted according to the specifications of 30, 50, and 75g, and they were stocked in groups of 10, 15 and 20 kg each. IV. Feeding and Feeding The seeds are not fed within 2 days before entering the box. The amount of fish eggs fed on the afternoon of the 3rd day is 1% of the seed weight. After every 6m2, the food intake reaches 6% after being fed for 2 hours. When the food intake reaches 7%, the compound feed can be added, and the compound feed is immersed in clean water for 1.5 hours, then the fresh material is evenly added, and the mixture is mixed again by the meat grinder, and the added amount of compound feed is 4% of the seed base. Fifth, water temperature, water quality during the breeding process, the water temperature is controlled at 20-30 °C is appropriate, early spring and late autumn water depth of about 1m, summer is 1.5m, if the water temperature is higher than 35 °C, then pumping low-temperature water to cool. In late October, the water temperature dropped to 15°C to arrest. Every 5-7 days, after the old pool water is discharged 10-20cm, new water is added.

LCZ696 (Valsartan/sacubitril) is a combination drug for use in heart failure developed by Novartis. It consists of the angiotensin receptor blocker valsartan and the neprilysin inhibitor sacubitril, in a 1:1 mixture by molecule count. It may be used instead of an ACE inhibitor or an angiotensin receptor blocker in people with heart failure with reduced ejection fraction. The combination is sometimes described as an "angiotensin receptor-neprilysin inhibitor" (ARNi).
It was approved under the FDA's priority review process on July 7, 2015. It is also approved in Europe.
We produce a series of complete intermediates for LCZ696, intermediate I (CAS No. 1426129-50-1) and intermediate II (CAS No. 1012341-50-2) etc.

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Lcz696 Intermediates

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